EnhancerDB
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Enhancers that regulate APLP2[ENSG00000084234.12]
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Chrom. Start End Enhancer ID TSS of gene Distance between enhancer and TSS Tissues that enhancer appears More
chr11 129828273 129846484 enh2109 129939732 93248
Prostate (PC-3) Liver (HepG2) Brain (SK-N-SH) Blood (OCI-LY7) Colon (HCT116) Adrenal Blood (Karpas-422) Lung (PC-9) Pancreas (Panc1) Neural Stem Cells (H9) Epithelial (MCF-7)
chr11 129857425 129868975 enh2110 129939732 70757
Liver (HepG2) Brain (SK-N-MC) Large Intestine Liver Blood (OCI-LY7) Muscle (A673) Placenta Blood (Karpas-422) Lung (PC-9) Pancreas Uterus
chr11 129871629 129871941 vista12154 129939732 67791
VISTA
chr11 129881283 129886590 enh60338 129939732 53142
Bone (Osteoblast) Blood (OCI-LY7)
chr11 129887349 129897615 enh14398 129939732 42117
Skin (Keratinocyte) Prostate (PC-3) Cervix (HeLa-S3) Prostate (RWPE1) Bone (Osteoblast) Blood (OCI-LY7) Placenta Colon (HCT116) Lung (PC-9) Muscle (Myoblast) Epithelial (MCF-7)
chr11 129900445 129915815 enh14399 129939732 23917
Bone Marrow (K562) Skin (Keratinocyte) Prostate (PC-3) Liver (HepG2) Large Intestine Prostate (RWPE1) Astrocyte Placenta Pancreas (Panc1) Epithelial (MCF-7)
chr11 129912030 129912233 vista12155 129939732 27499
VISTA
chr11 129913538 129913657 vista12156 129939732 26075
VISTA
chr11 129918305 129922455 enh109529 129939732 17277
Stomach
chr11 129920255 129920483 vista12157 129939732 19249
VISTA
chr11 129920821 129921218 vista12158 129939732 18514
VISTA
chr11 129923502 129927730 enh43659 129939732 12002
Muscle (Myotube)
chr11 129925505 129925678 vista12159 129939732 14054
VISTA
chr11 129942098 129942391 vista12160 129939732 2366
VISTA
chr11 129945665 129949815 enh90924 129939732 5933
Bone Marrow (K562)
chr11 129950466 129954694 enh60339 129939732 10734
Blood (OCI-LY7)
chr11 129955528 129969035 enh60340 129939732 15796
Liver (HepG2) Cervix (HeLa-S3) Brain (SK-N-MC) Blood (OCI-LY7) Muscle (A673) Heart
chr11 129982265 129990518 enh60341 129939732 42533
Liver (HepG2) Blood (OCI-LY7) Blood (GM12878) Lung (PC-9) Neural Stem Cells (H9)
chr11 129993921 129994394 vista12161 129939732 54189
VISTA
chr11 130004100 130008595 enh64546 129939732 64368
Heart
chr11 130012145 130023810 enh14400 129939732 72413
Prostate (PC-3) Cervix (HeLa-S3) Blood (T-cell) Liver Blood (OCI-LY7) Blood (GM12878) Stomach Placenta Colon (HCT116) Peripheral Blood (MM.1S) Lung (PC-9) Pancreas Thymus Heart
chr11 130016455 130016576 vista12162 129939732 76723
VISTA
chr11 130029525 130054216 enh14401 129939732 89793
Astrocyte Colon (HCT116) Adrenal Pancreas Epithelial (MCF-7) Stomach Skin (Keratinocyte) Blood (OCI-LY7) Thyroid Peripheral Blood (MM.1S) Thymus Prostate (PC-3) Cervix (HeLa-S3) Large Intestine Esophagus Placenta Lung (PC-9) Liver (HepG2) Prostate (RWPE1) Lung Heart
chr11 130036262 130036668 vista12163 129939732 96530
VISTA
Transcript facotrs that regulate APLP2[ENSG00000084234.12]
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Chrom. Start End TF name Source Predicted site? Tissue TSS of gene Distance between TFBS and gene id More
chr11 129941736 129942352 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 129939732 2004 108007977
chr11 129941759 129942303 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 129939732 2027 108007978
chr11 129941858 129942148 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 129939732 2126 108007979
chr11 129941897 129942333 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 129939732 2165 108007980
chr11 129941904 129942164 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 129939732 2172 108007981
chr11 129941915 129942205 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 129939732 2183 108007982
chr11 129941932 129942272 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 129939732 2200 108007983
chr11 129941934 129942250 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 129939732 2202 108007984
chr11 129941941 129942145 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 129939732 2209 108007985
chr11 129941950 129942330 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 129939732 2218 108007986
chr11 129941961 129942321 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 129939732 2229 108007987
chr11 129941965 129942241 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 129939732 2233 108007988
chr11 129941965 129942341 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 129939732 2233 108007989
chr11 129942015 129942275 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 129939732 2283 108007990
chr11 129942141 129942147 ZNF354C JASPAR yes 129939732 2409 114158524
chr11 129942145 129942156 NFE2L2 JASPAR yes 129939732 2413 114158525
chr11 129942159 129942173 SPI1 JASPAR yes 129939732 2427 114158526
chr11 129942159 129942174 STAT2 JASPAR yes 129939732 2427 114158527
chr11 129942161 129942173 ELF4 JASPAR yes 129939732 2429 114158528
chr11 129942162 129942173 SPDEF JASPAR yes 129939732 2430 114158529
chr11 129942163 129942172 ELK4 JASPAR yes 129939732 2431 114158530
chr11 129942163 129942173 ELK1 JASPAR yes 129939732 2431 114158531
chr11 129942163 129942173 ELK3 JASPAR yes 129939732 2431 114158532
chr11 129942163 129942173 ERF JASPAR yes 129939732 2431 114158533
chr11 129942163 129942173 ETV1 JASPAR yes 129939732 2431 114158534
chr11 129942163 129942173 ETV4 JASPAR yes 129939732 2431 114158535
chr11 129942182 129942186 NFE TRANSFAC yes 129939732 2450 114158536
chr11 129942188 129942192 YY1 TRANSFAC yes 129939732 2456 114158537
chr11 129942207 129942211 YY1 TRANSFAC yes 129939732 2475 114158538
chr11 129942221 129942232 STAT1 JASPAR yes 129939732 2489 114158539
chr11 129942221 129942232 STAT3 JASPAR yes 129939732 2489 114158540
chr11 129942227 129942237 RELA JASPAR yes 129939732 2495 114158541
chr11 129942227 129942241 STAT1 JASPAR yes 129939732 2495 114158542
chr11 129942227 129942245 IRF2 JASPAR yes 129939732 2495 114158543
chr11 129942228 129942240 IRF1 JASPAR yes 129939732 2496 114158544
chr11 129942278 129942284 SOX10 JASPAR yes 129939732 2546 114158545
chr11 129942295 129942307 PKNOX1 JASPAR yes 129939732 2563 114158546
chr11 129942295 129942307 PKNOX2 JASPAR yes 129939732 2563 114158547
chr11 129942295 129942307 TGIF1 JASPAR yes 129939732 2563 114158548
chr11 129942295 129942307 TGIF2 JASPAR yes 129939732 2563 114158549
chr11 129942296 129942305 SNAI2 JASPAR yes 129939732 2564 114158550
chr11 129942296 129942306 FIGLA JASPAR yes 129939732 2564 114158551
chr11 129942296 129942306 MSC JASPAR yes 129939732 2564 114158552
chr11 129942310 129942586 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 129939732 2578 108007991
chr11 129942319 129942340 REST JASPAR yes 129939732 2587 114158553
chr11 129942351 129942365 GATA2 JASPAR yes 129939732 2619 114158554
chr11 129942363 129942384 IRF1 JASPAR yes 129939732 2631 114158555
chr11 129942364 129942385 IRF1 JASPAR yes 129939732 2632 114158556
chr11 129942365 129942386 IRF1 JASPAR yes 129939732 2633 114158557
chr11 129942366 129942381 FOXP1 JASPAR yes 129939732 2634 114158558
chr11 129942366 129942387 IRF1 JASPAR yes 129939732 2634 114158559
chr11 129942367 129942388 IRF1 JASPAR yes 129939732 2635 114158560
chr11 129942368 129942383 FOXP1 JASPAR yes 129939732 2636 114158561
chr11 129942368 129942389 IRF1 JASPAR yes 129939732 2636 114158562
chr11 129942369 129942384 FOXP1 JASPAR yes 129939732 2637 114158563
chr11 129942369 129942390 IRF1 JASPAR yes 129939732 2637 114158564
chr11 129942370 129942385 FOXP1 JASPAR yes 129939732 2638 114158565
chr11 129942371 129942386 FOXP1 JASPAR yes 129939732 2639 114158566
chr11 129942372 129942387 FOXP1 JASPAR yes 129939732 2640 114158567
chr11 129942373 129942388 FOXP1 JASPAR yes 129939732 2641 114158568
chr11 129942374 129942389 FOXP1 JASPAR yes 129939732 2642 114158569
chr11 129942375 129942390 FOXP1 JASPAR yes 129939732 2643 114158570
chr11 129942376 129942391 FOXP1 JASPAR yes 129939732 2644 114158571
SNPs associated with APLP2[ENSG00000084234.12], confirmed by eQTL
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Chrom. Position dbSNP ID Reference Allele Alternative Allele Distance between TSS and SNP Tissue q Value id More
chr11 130246302 rs112603486 T C 231603 Heart 0.270028 2370260
chr11 130914970 rs142878238 T C 900271 Heart 0.224511 2375767
chr11 130672225 rs34063616 A C 657526 Pancreas 0.409855 2374143
chr11 130420642 rs397759791 T TAAG 405943 Thyroid 0.234451 2371819
chr11 130754633 rs75070285 C T 739934 Lung 0.247887 2375071
chr11 130903642 rs10750460 C T 888943 Stomach 0.391304 2375627
Details of APLP2[ENSG00000084234.12]
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Genomic Location chr11:129939732-130014699[+]
TSS 129939732
Gene Name APLP2
Ensembl ID ENSG00000084234.12
ENTREZID 334
Uniprot
B4E3I5
Q06481
A0A140VJE9
Protein Name
Alternative protein APLP2
Amyloid beta
Amyloid-like protein 2
Expression levels of APLP2[ENSG00000084234.12]
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