EnhancerDB
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Enhancers that regulate NEDD4L[ENSG00000049759.12]
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Chrom. Start End Enhancer ID TSS of gene Distance between enhancer and TSS Tissues that enhancer appears More
chr18 55607383 55616589 enh58828 55711599 95010
Skin (Keratinocyte) Prostate (PC-3) Cervix (HeLa-S3) Prostate (RWPE1) Esophagus Peripheral Blood (MM.1S)
chr18 55617325 55624435 enh52772 55711599 87164
Thyroid Large Intestine
chr18 55627171 55634695 enh4865 55711599 76904
Muscle (Myoblast) Muscle (Myotube) Blood (Karpas-422) Stomach
chr18 55636005 55640635 enh17734 55711599 70964
Placenta
chr18 55645905 55650395 enh104468 55711599 61204
Peripheral Blood (MM.1S) Stomach
chr18 55661105 55667315 enh4866 55711599 44284
Blood (Karpas-422)
chr18 55667805 55675794 enh32732 55711599 35805
Skin (Keratinocyte) Prostate (PC-3) Liver (HepG2) Astrocyte Bone (Osteoblast) Colon (HCT116) Lung (PC-9) Muscle (Myoblast)
chr18 55671810 55671869 vista27571 55711599 39730
VISTA
chr18 55677725 55693595 enh4867 55711599 18004
Prostate (PC-3) Liver (HepG2) Cervix (HeLa-S3) Large Intestine Esophagus Blood (OCI-LY7) Stomach Peripheral Blood (MM.1S) Blood (Karpas-422) Lung (PC-9) Pancreas Spleen Epithelial (MCF-7)
chr18 55687218 55687390 vista27572 55711599 24209
VISTA
chr18 55710685 55710979 vista27573 55711599 620
VISTA
chr18 55717105 55721555 enh32733 55711599 5506
Liver (HepG2) Astrocyte Stomach Peripheral Blood (MM.1S) Lung (PC-9) Epithelial (MCF-7)
chr18 55724025 55728175 enh91197 55711599 12426
Bone Marrow (K562)
chr18 55732985 55739395 enh69481 55711599 21386
Liver (HepG2) Neural Stem Cells (H9) Stomach
chr18 55741352 55750035 enh52773 55711599 29753
Bone Marrow (K562) Skin (Keratinocyte) Large Intestine Esophagus Stomach Lung (PC-9) Epithelial (MCF-7)
chr18 55752994 55757764 enh58829 55711599 41395
Bone Marrow (K562) Skin (Keratinocyte) Prostate (PC-3) Cervix (HeLa-S3) Stomach Lung (PC-9) Pancreas Neural Stem Cells (H9) Epithelial (MCF-7)
chr18 55756032 55756268 vista27574 55711599 44433
VISTA
chr18 55760945 55776155 enh4868 55711599 49346
Liver (HepG2) Large Intestine Liver Astrocyte Thyroid Peripheral Blood (MM.1S) Adrenal Blood (Karpas-422) Lung (PC-9) Pancreas Stomach
chr18 55768514 55768737 vista27575 55711599 56915
VISTA
chr18 55783285 55791395 enh52774 55711599 71686
Bone Marrow (K562) Prostate (PC-3) Liver (HepG2) Large Intestine Breast Lung (PC-9) Pancreas Stomach
chr18 55793985 55814175 enh17735 55711599 82386
Liver (HepG2) Brain (SK-N-SH) Large Intestine Lung (PC-9) Placenta Muscle (Myoblast) Pancreas Muscle (Myotube) Neural Stem Cells (H9) Stomach
chr18 55803829 55804070 vista27576 55711599 92230
VISTA
Transcript facotrs that regulate NEDD4L[ENSG00000049759.12]
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Chrom. Start End TF name Source Predicted site? Tissue TSS of gene Distance between TFBS and gene id More
chr18 55710574 55710884 POU2F2 UCSC Txn Factor no Conserved 55711599 715 108338031
chr18 55710585 55711021 ZZZ3 ENCODE Uniform TFBS no Blood (GM12878) 55711599 578 108338032
chr18 55710650 55710840 ZZZ3 ENCODE Uniform TFBS no Blood (GM12878) 55711599 759 108338033
chr18 55710658 55711194 ZZZ3 ENCODE Uniform TFBS no Blood (GM12878) 55711599 405 108338034
chr18 55710669 55711109 TCF7L2 ENCODE Uniform TFBS no Pancreas (Panc1) 55711599 490 108338035
chr18 55710686 55710691 SP1 TRANSFAC yes 55711599 908 42713675
chr18 55710689 55710694 ETS2 TRANSFAC yes 55711599 905 42713676
chr18 55710689 55711125 ZZZ3 ENCODE Uniform TFBS no Blood (GM12878) 55711599 474 108338036
chr18 55710690 55711126 ZZZ3 ENCODE Uniform TFBS no Blood (GM12878) 55711599 473 108338037
chr18 55710692 55711082 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 55711599 517 108338038
chr18 55710701 55711071 ZZZ3 ENCODE Uniform TFBS no Blood (GM12878) 55711599 528 108338039
chr18 55710707 55710983 EGR1 UCSC Txn Factor no Conserved 55711599 616 108338040
chr18 55710707 55710983 ZNF143 ENCODE Uniform TFBS no Embryonic Stem Cell Line (H1-hESC) 55711599 616 108338041
chr18 55710708 55710958 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 55711599 641 108338042
chr18 55710712 55710724 PROX1 JASPAR yes 55711599 875 42713677
chr18 55710721 55711085 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 55711599 514 108338043
chr18 55710723 55711133 ZZZ3 ENCODE Uniform TFBS no Blood (GM12878) 55711599 466 108338044
chr18 55710724 55710737 POU2F2 JASPAR yes 55711599 862 42713678
chr18 55710724 55710738 POU1F1 JASPAR yes 55711599 861 42713679
chr18 55710725 55710737 POU3F1 JASPAR yes 55711599 862 42713680
chr18 55710725 55710737 POU3F2 JASPAR yes 55711599 862 42713681
chr18 55710725 55710738 POU3F3 JASPAR yes 55711599 861 42713682
chr18 55710726 55710730 YY1 TRANSFAC yes 55711599 869 42713683
chr18 55710726 55710738 POU2F1 JASPAR yes 55711599 861 42713684
chr18 55710727 55710734 POU2F1 TRANSFAC yes 55711599 865 42713685
chr18 55710727 55710734 POU2F2C TRANSFAC yes 55711599 865 42713686
chr18 55710727 55710734 POU2F2 TRANSFAC yes 55711599 865 42713687
chr18 55710727 55710735 POU2F1 TRANSFAC yes 55711599 864 42713688
chr18 55710727 55710736 POU3F4 JASPAR yes 55711599 863 42713689
chr18 55710727 55710736 POU5F1B JASPAR yes 55711599 863 42713690
chr18 55710727 55711107 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 55711599 492 108338045
chr18 55710732 55710744 POU2F1 JASPAR yes 55711599 855 42713691
chr18 55710732 55710746 POU1F1 JASPAR yes 55711599 853 42713692
chr18 55710733 55710745 POU3F1 JASPAR yes 55711599 854 42713693
chr18 55710733 55710745 POU3F2 JASPAR yes 55711599 854 42713694
chr18 55710733 55710746 POU2F2 JASPAR yes 55711599 853 42713695
chr18 55710733 55711321 CTCF UCSC Txn Factor no Conserved 55711599 278 108338046
chr18 55710734 55710743 POU3F4 JASPAR yes 55711599 856 42713696
chr18 55710734 55710743 POU5F1B JASPAR yes 55711599 856 42713697
chr18 55710736 55710742 TCF4 TRANSFAC yes 55711599 857 42713698
chr18 55710742 55710747 GATA2 JASPAR yes 55711599 852 42713699
chr18 55710745 55710748 MYB TRANSFAC yes 55711599 851 42713700
chr18 55710747 55711143 ZZZ3 ENCODE Uniform TFBS no Cervix (HeLa-S3) 55711599 456 108338047
chr18 55710749 55710763 PAX6 JASPAR yes 55711599 836 42713701
chr18 55710751 55711151 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 55711599 448 108338048
chr18 55710753 55711013 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 55711599 586 108338049
chr18 55710758 55711138 ZZZ3 ENCODE Uniform TFBS no Blood (GM12878) 55711599 461 108338050
chr18 55710764 55711020 FOXA1 UCSC Txn Factor no Conserved 55711599 579 108338051
chr18 55710766 55710770 YY1 TRANSFAC yes 55711599 829 42713702
chr18 55710766 55711013 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 55711599 586 108338052
chr18 55710771 55711041 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 55711599 558 108338053
chr18 55710771 55711057 SMC3 UCSC Txn Factor no Conserved 55711599 542 108338054
chr18 55710775 55711105 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 55711599 494 108338055
chr18 55710776 55710906 ZZZ3 ENCODE Uniform TFBS no Blood (GM12878) 55711599 693 108338056
chr18 55710776 55711046 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 55711599 553 108338057
chr18 55710779 55710996 FOXA2 UCSC Txn Factor no Conserved 55711599 603 108338058
chr18 55710779 55710996 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 55711599 603 108338059
chr18 55710780 55711070 ZNF143 ENCODE Uniform TFBS no Embryonic Stem Cell Line (H1-hESC) 55711599 529 108338060
chr18 55710782 55711102 ZZZ3 ENCODE Uniform TFBS no Blood (GM12878) 55711599 497 108338061
chr18 55710783 55711047 ZZZ3 ENCODE Uniform TFBS no Cervix (HeLa-S3) 55711599 552 108338062
chr18 55710785 55711121 ZNF143 ENCODE Uniform TFBS no Embryonic Stem Cell Line (H1-hESC) 55711599 478 108338063
chr18 55710787 55711057 ZZZ3 ENCODE Uniform TFBS no Blood (GM12878) 55711599 542 108338064
chr18 55710792 55711056 ZZZ3 ENCODE Uniform TFBS no Blood (GM12878) 55711599 543 108338065
chr18 55710797 55711057 RAD21 UCSC Txn Factor no Conserved 55711599 542 108338066
chr18 55710802 55711032 ZBTB33 ENCODE Uniform TFBS no Lung (A549) 55711599 567 108338067
chr18 55710803 55710809 TCF1 TRANSFAC yes 55711599 790 42713703
chr18 55710814 55711042 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 55711599 557 108338068
chr18 55710815 55711008 ZNF217 ENCODE Uniform TFBS no Epithelial (MCF-7) 55711599 591 108338069
chr18 55710817 55710821 NFE TRANSFAC yes 55711599 778 42713704
chr18 55710820 55711011 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 55711599 588 108338070
chr18 55710822 55710842 RREB1 JASPAR yes 55711599 757 42713705
chr18 55710826 55711021 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 55711599 578 108338071
chr18 55710828 55710990 ZBTB33 ENCODE Uniform TFBS no Lung (A549) 55711599 609 108338072
chr18 55710831 55711000 ZZZ3 ENCODE Uniform TFBS no Cervix (HeLa-S3) 55711599 599 108338073
chr18 55710834 55710839 SP1 TRANSFAC yes 55711599 760 42713706
chr18 55710834 55711034 ZNF143 ENCODE Uniform TFBS no Embryonic Stem Cell Line (H1-hESC) 55711599 565 108338074
chr18 55710835 55711013 ZZZ3 ENCODE Uniform TFBS no Cervix (HeLa-S3) 55711599 586 108338075
chr18 55710844 55710847 MYB TRANSFAC yes 55711599 752 42713707
chr18 55710845 55711011 ZZZ3 ENCODE Uniform TFBS no Blood (GM12878) 55711599 588 108338076
chr18 55710849 55710857 SP1 TRANSFAC yes 55711599 742 42713708
chr18 55710849 55710860 NRF1 JASPAR yes 55711599 739 42713709
chr18 55710850 55710855 SP1 TRANSFAC yes 55711599 744 42713710
chr18 55710851 55710856 SP1 TRANSFAC yes 55711599 743 42713711
chr18 55710854 55710973 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 55711599 626 108338077
chr18 55710860 55710872 FOXC2 JASPAR yes 55711599 727 42713712
chr18 55710862 55710995 ZBTB33 ENCODE Uniform TFBS no Colon (HCT116) 55711599 604 108338078
chr18 55710868 55710874 TCF4 TRANSFAC yes 55711599 725 42713713
chr18 55710873 55711197 ZNF143 ENCODE Uniform TFBS no Embryonic Stem Cell Line (H1-hESC) 55711599 402 108338079
chr18 55710880 55710972 ZZZ3 ENCODE Uniform TFBS no Blood (GM12878) 55711599 627 108338080
chr18 55710880 55710997 ZZZ3 ENCODE Uniform TFBS no Cervix (HeLa-S3) 55711599 602 108338081
chr18 55710881 55710952 ZNF143 ENCODE Uniform TFBS no Embryonic Stem Cell Line (H1-hESC) 55711599 647 108338082
chr18 55710895 55710906 YY2 JASPAR yes 55711599 693 42713714
chr18 55710904 55711420 ZZZ3 ENCODE Uniform TFBS no Cervix (HeLa-S3) 55711599 179 108338083
chr18 55710907 55710919 GLI2 JASPAR yes 55711599 680 42713715
chr18 55710916 55710934 ESR2 JASPAR yes 55711599 665 42713716
chr18 55710916 55710936 PPARG JASPAR yes 55711599 663 42713717
chr18 55710918 55710933 ESR2 JASPAR yes 55711599 666 42713718
chr18 55710918 55710938 ESR1 JASPAR yes 55711599 661 42713719
chr18 55710919 55710923 LFA1 TRANSFAC yes 55711599 676 42713720
chr18 55710950 55710955 SP1 TRANSFAC yes 55711599 644 42713721
chr18 55710954 55710975 REST JASPAR yes 55711599 624 42713722
chr18 55710955 55710974 REST JASPAR yes 55711599 625 42713723
SNPs associated with NEDD4L[ENSG00000049759.12], confirmed by eQTL
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Chrom. Position dbSNP ID Reference Allele Alternative Allele Distance between TSS and SNP Tissue q Value id More
chr18 55917474 rs397972034 C CA 0 Heart 0.0029901 5283158
chr18 55936401 rs56883467 G A 0 Heart 0.398856 5283331
chr18 56383431 rs8084579 C T 314659 Lung 0.0234273 5287164
chr18 55200681 rs76282601 C T 510918 Stomach 0.0507279 5276495
chr18 55717494 rs4072561 A G 0 Adrenal 6.08762e-10 5280791
Details of NEDD4L[ENSG00000049759.12]
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Genomic Location chr18:55711599-56068772[+]
TSS 55711599
Gene Name NEDD4L
Ensembl ID ENSG00000049759.12
ENTREZID 23327
Uniprot
B7Z2P9
A0A024R281
B7Z6K0
Q96PU5
A0A024R2A4
Protein Name
E3 ubiquitin-protein ligase
E3 ubiquitin-protein ligase NEDD4-like
NEDD4-2 minus WW2,3 variant
Expression levels of NEDD4L[ENSG00000049759.12]
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