EnhancerDB
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Enhancers that regulate SHC2[ENSG00000129946.6]
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Chrom. Start End Enhancer ID TSS of gene Distance between enhancer and TSS Tissues that enhancer appears More
chr19 380759 380771 vista28077 460996 80225
VISTA
chr19 381942 386244 enh94982 460996 74752
Muscle (Myoblast)
chr19 383028 383243 vista28078 460996 77753
VISTA
chr19 384369 384669 vista28079 460996 76327
VISTA
chr19 387021 391473 enh102304 460996 69523
Embryonic Stem Cell Line (H1-hESC)
chr19 399579 408133 enh115680 460996 52863
Brain (SK-N-SH)
chr19 417829 418007 vista28080 460996 42989
VISTA
chr19 437457 437640 vista28081 460996 23356
VISTA
chr19 441805 442098 vista28082 460996 18898
VISTA
chr19 445179 445348 vista28083 460996 15648
VISTA
chr19 445245 450091 enh65162 460996 10905
Uterus Heart
chr19 461817 462164 vista28084 460996 821
VISTA
chr19 481673 481793 vista28085 460996 20677
VISTA
chr19 485856 486161 vista28086 460996 24860
VISTA
chr19 488227 488667 vista28087 460996 27231
VISTA
chr19 489577 495615 enh89912 460996 28581
Prostate (RWPE1) Stomach
chr19 508752 518855 enh17832 460996 47756
Bone Marrow (K562) Liver (HepG2) Stomach Placenta Heart Blood (T-cell) Epithelial (MCF-7)
chr19 510583 510951 vista28088 460996 49587
VISTA
chr19 511222 511648 vista28089 460996 50226
VISTA
chr19 522045 526355 enh17833 460996 61049
Placenta Liver (HepG2)
chr19 532930 533293 vista28090 460996 71934
VISTA
chr19 552765 561015 enh17834 460996 91769
Bone Marrow (K562) Liver (HepG2) Cervix (HeLa-S3) Epithelial (MCF-7) Prostate (RWPE1) Ovary Lung Stomach Muscle (A673) Placenta Colon (HCT116) Uterus Heart
chr19 555976 556322 vista28091 460996 94980
VISTA
Transcript facotrs that regulate SHC2[ENSG00000129946.6]
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Chrom. Start End TF name Source Predicted site? Tissue TSS of gene Distance between TFBS and gene id More
chr19 459410 462486 ZNF274 GTRD no Bone Marrow (K562) 460996 1490 108343761
chr19 459431 462639 TCF7L2 GTRD no Colon (HCT116) 460996 1565 108343762
chr19 459554 462770 ZNF274 GTRD no Bone Marrow (K562) 460996 1442 108343763
chr19 459590 462570 TCF7L2 GTRD no Colon (HCT116) 460996 1406 108343764
chr19 459642 462682 TCF7L2 GTRD no Colon (HCT116) 460996 1354 108343765
chr19 459642 462807 TCF7L2 GTRD no Colon (HCT116) 460996 1354 108343766
chr19 459656 462658 TCF7L2 GTRD no Colon (HCT116) 460996 1340 108343767
chr19 459683 462703 ZNF274 GTRD no Liver (HepG2) 460996 1313 108343768
chr19 459838 462603 TCF7L2 GTRD no Colon (HCT116) 460996 1158 108343769
chr19 460026 462291 TCF7L2 GTRD no Colon (HCT116) 460996 970 108343770
chr19 460825 462425 TCF7L2 GTRD no Colon (HCT116) 460996 171 108343771
chr19 460842 462365 ZNF274 GTRD no Liver (HepG2) 460996 154 108343772
chr19 461294 462390 ZNF274 GTRD no Liver (HepG2) 460996 298 108343773
chr19 461311 462576 ZNF274 GTRD no Bone Marrow (K562) 460996 315 108343774
chr19 461324 462441 ZNF274 GTRD no Liver (HepG2) 460996 328 108343775
chr19 461497 462167 ZNF143 ENCODE Uniform TFBS no Embryonic Stem Cell Line (H1-hESC) 460996 501 108343776
chr19 461529 462571 ZNF274 GTRD no Cervix (HeLa-S3) 460996 533 108343777
chr19 461535 462584 TCF7L2 GTRD no Colon (HCT116) 460996 539 108343778
chr19 461536 462816 ZNF274 GTRD no Liver (HepG2) 460996 540 108343779
chr19 461540 462797 ZNF274 GTRD no Liver (HepG2) 460996 544 108343780
chr19 461554 462301 ZNF274 GTRD no Liver (HepG2) 460996 558 108343781
chr19 461564 462589 ZNF274 GTRD no Liver (HepG2) 460996 568 108343782
chr19 461569 462968 ZNF274 GTRD no Cervix (HeLa-S3) 460996 573 108343783
chr19 461575 462652 ZNF274 GTRD no Bone Marrow (K562) 460996 579 108343784
chr19 461590 462324 ZNF274 GTRD no Liver (HepG2) 460996 594 108343785
chr19 461591 462432 ZNF274 GTRD no Liver (HepG2) 460996 595 108343786
chr19 461594 461930 ZNF274 GTRD no Bone Marrow (K562) 460996 598 108343787
chr19 461608 462751 ZNF274 GTRD no Liver (HepG2) 460996 612 108343788
chr19 461608 462841 ZNF274 GTRD no Liver (HepG2) 460996 612 108343789
chr19 461632 462421 ZNF274 GTRD no Bone Marrow (K562) 460996 636 108343790
chr19 461632 462427 ZNF274 GTRD no Liver (HepG2) 460996 636 108343791
chr19 461646 462588 ZNF274 GTRD no Bone Marrow (K562) 460996 650 108343792
chr19 461650 462633 ZNF274 GTRD no Bone Marrow (K562) 460996 654 108343793
chr19 461667 462412 ZNF274 GTRD no Bone Marrow (K562) 460996 671 108343794
chr19 461676 462485 ZNF274 GTRD no Bone Marrow (K562) 460996 680 108343795
chr19 461678 462133 ZNF274 GTRD no Cervix (HeLa-S3) 460996 682 108343796
chr19 461689 462330 ZNF274 GTRD no Bone Marrow (K562) 460996 693 108343797
chr19 461696 461913 ZNF274 GTRD no Liver (HepG2) 460996 700 108343798
chr19 461699 462407 ZNF274 GTRD no Bone Marrow (K562) 460996 703 108343799
chr19 461701 461850 ZNF274 GTRD no Liver (HepG2) 460996 705 108343800
chr19 461705 462273 ZNF274 GTRD no Liver (HepG2) 460996 709 108343801
chr19 461715 462179 ZZZ3 ENCODE Uniform TFBS no Cervix (HeLa-S3) 460996 719 108343802
chr19 461717 462471 ZNF274 GTRD no Liver (HepG2) 460996 721 108343803
chr19 461724 462326 ZNF274 GTRD no Bone Marrow (K562) 460996 728 108343804
chr19 461729 462377 ZNF274 GTRD no Bone Marrow (K562) 460996 733 108343805
chr19 461735 462407 ZNF274 GTRD no Liver (HepG2) 460996 739 108343806
chr19 461737 462234 ZNF143 GTRD no Epithelial (MCF-7) 460996 741 108343807
chr19 461737 462259 ZNF274 GTRD no Cervix (HeLa-S3) 460996 741 108343808
chr19 461743 462446 TCF7L2 GTRD no Colon (HCT116) 460996 747 108343809
chr19 461746 462301 ZNF274 GTRD no Liver (HepG2) 460996 750 108343810
chr19 461748 462304 ZNF274 GTRD no Liver (HepG2) 460996 752 108343811
chr19 461751 462278 ZNF274 GTRD no Liver (HepG2) 460996 755 108343812
chr19 461751 462787 ZNF274 GTRD no Bone Marrow (K562) 460996 755 108343813
chr19 461756 462126 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 460996 760 108343814
chr19 461757 462218 ZNF274 GTRD no Bone Marrow (K562) 460996 761 108343815
chr19 461757 462401 ZNF274 GTRD no Bone Marrow (K562) 460996 761 108343816
chr19 461773 462264 ZNF274 GTRD no Cervix (HeLa-S3) 460996 777 108343817
chr19 461778 462163 ZNF274 GTRD no Cervix (HeLa-S3) 460996 782 108343818
chr19 461781 462246 SOX2 GTRD no Neural Stem Cells (H9) 460996 785 108343819
chr19 461788 462361 TCF7L2 GTRD no Colon (HCT116) 460996 792 108343820
chr19 461791 462337 ZNF274 GTRD no Liver (HepG2) 460996 795 108343821
chr19 461794 462302 ZNF274 GTRD no Bone Marrow (K562) 460996 798 108343822
chr19 461795 462522 TCF7L2 UCSC Txn Factor no Conserved 460996 799 108343823
chr19 461796 462008 SOX2 GTRD no Neural Stem Cells (H9) 460996 800 108343824
chr19 461797 462270 TCF7L2 GTRD no Colon (HCT116) 460996 801 108343825
chr19 461805 462367 ZNF274 GTRD no Bone Marrow (K562) 460996 809 108343826
chr19 461806 462274 TCF7L2 GTRD no Colon (HCT116) 460996 810 108343827
chr19 461809 462410 ZNF274 GTRD no Bone Marrow (K562) 460996 813 108343828
chr19 461811 462198 ZNF274 GTRD no Liver (HepG2) 460996 815 108343829
chr19 461813 462707 ZNF274 GTRD no Bone Marrow (K562) 460996 817 108343830
chr19 461814 462270 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 460996 818 108343831
chr19 461815 462319 ZZZ3 ENCODE Uniform TFBS no Cervix (HeLa-S3) 460996 819 108343832
chr19 461816 462206 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 460996 820 108343833
chr19 461816 462716 ZNF274 GTRD no Bone Marrow (K562) 460996 820 108343834
chr19 461823 462271 ZNF274 GTRD no Liver (HepG2) 460996 827 108343835
chr19 461830 462095 ZNF274 GTRD no Liver (HepG2) 460996 834 108343836
chr19 461830 462103 ZNF274 GTRD no Liver (HepG2) 460996 834 108343837
chr19 461832 462315 ZNF274 GTRD no Bone Marrow (K562) 460996 836 108343838
chr19 461833 462257 ZNF274 GTRD no Liver (HepG2) 460996 837 108343839
chr19 461833 462503 ZNF143 ENCODE Uniform TFBS no Embryonic Stem Cell Line (H1-hESC) 460996 837 108343840
chr19 461834 461839 ETS2 TRANSFAC yes 460996 838 70775939
chr19 461842 462138 ZNF274 GTRD no Liver (HepG2) 460996 846 108343841
chr19 461842 462288 ZNF274 GTRD no Liver (HepG2) 460996 846 108343842
chr19 461847 462611 P63 GTRD no Skin (Keratinocyte) 460996 851 108343843
chr19 461855 461873 ESR2 JASPAR yes 460996 859 70775940
chr19 461856 461873 ESR1 JASPAR yes 460996 860 70775941
chr19 461857 461872 ESR2 JASPAR yes 460996 861 70775942
chr19 461857 461877 ESR1 JASPAR yes 460996 861 70775943
chr19 461861 462401 ZNF274 GTRD no Bone Marrow (K562) 460996 865 108343844
chr19 461863 461867 NFE TRANSFAC yes 460996 867 70775944
chr19 461867 462491 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 460996 871 108343845
chr19 461873 462213 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 460996 877 108343846
chr19 461873 462297 TCF7L2 GTRD no Colon (HCT116) 460996 877 108343847
chr19 461876 461886 SP1 JASPAR yes 460996 880 70775945
chr19 461877 461887 SP1 JASPAR yes 460996 881 70775946
chr19 461877 462333 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 460996 881 108343848
chr19 461879 462539 ZZZ3 ENCODE Uniform TFBS no Cervix (HeLa-S3) 460996 883 108343849
chr19 461882 462252 ZZZ3 ENCODE Uniform TFBS no Cervix (HeLa-S3) 460996 886 108343850
chr19 461887 462503 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 460996 891 108343851
chr19 461891 462937 ZNF274 GTRD no Bone Marrow (K562) 460996 895 108343852
chr19 461893 462313 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 460996 897 108343853
chr19 461894 462116 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 460996 898 108343854
chr19 461897 462393 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 460996 901 108343855
chr19 461898 462118 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 460996 902 108343856
chr19 461898 462154 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 460996 902 108343857
chr19 461898 462233 ZNF274 GTRD no Bone Marrow (K562) 460996 902 108343858
chr19 461900 462100 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 460996 904 108343859
chr19 461900 462300 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 460996 904 108343860
chr19 461901 461912 NFKB1 JASPAR yes 460996 905 70775947
chr19 461901 462177 ZNF274 GTRD no Bone Marrow (K562) 460996 905 108343861
chr19 461904 462220 ZNF274 ENCODE Uniform TFBS no Liver (HepG2) 460996 908 108343862
chr19 461906 462150 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 460996 910 108343863
chr19 461907 461924 RXRA JASPAR yes 460996 911 70775948
chr19 461909 462410 ZNF274 GTRD no Bone Marrow (K562) 460996 913 108343864
chr19 461909 462459 ZNF274 GTRD no Bone Marrow (K562) 460996 913 108343865
chr19 461910 462190 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 460996 914 108343866
chr19 461912 461922 ID4 JASPAR yes 460996 916 70775949
chr19 461912 461922 TCF3 JASPAR yes 460996 916 70775950
chr19 461912 461922 TCF4 JASPAR yes 460996 916 70775951
chr19 461913 461922 SNAI2 JASPAR yes 460996 917 70775952
chr19 461914 461919 USF2 TRANSFAC yes 460996 918 70775953
chr19 461917 461923 NFE2 TRANSFAC yes 460996 921 70775954
chr19 461918 462298 ZZZ3 ENCODE Uniform TFBS no Cervix (HeLa-S3) 460996 922 108343867
chr19 461919 461928 SP1 TRANSFAC yes 460996 923 70775955
chr19 461920 461926 SP1 TRANSFAC yes 460996 924 70775956
chr19 461920 461930 SP1 JASPAR yes 460996 924 70775957
chr19 461921 461928 SP1 TRANSFAC yes 460996 925 70775958
chr19 461922 461927 SP1 TRANSFAC yes 460996 926 70775959
chr19 461922 461928 SP1 TRANSFAC yes 460996 926 70775960
chr19 461923 461934 TFAP2A JASPAR yes 460996 927 70775961
chr19 461923 461934 TFAP2B JASPAR yes 460996 927 70775962
chr19 461923 461934 TFAP2C JASPAR yes 460996 927 70775963
chr19 461931 462399 ZNF274 GTRD no Bone Marrow (K562) 460996 935 108343868
chr19 461939 461954 STAT1 JASPAR yes 460996 943 70775964
chr19 461941 461952 STAT1 JASPAR yes 460996 945 70775965
chr19 461941 461952 STAT3 JASPAR yes 460996 945 70775966
chr19 461950 461956 SOX10 JASPAR yes 460996 954 70775967
chr19 461953 462316 ZNF274 GTRD no Liver (HepG2) 460996 957 108343869
chr19 461955 461961 MAZ TRANSFAC yes 460996 959 70775968
chr19 461959 461964 SP1 TRANSFAC yes 460996 963 70775969
chr19 461959 461966 SP1 TRANSFAC yes 460996 963 70775970
chr19 461964 462188 ZBTB33 ENCODE Uniform TFBS no Colon (HCT116) 460996 968 108343870
chr19 461971 462114 ZNF274 GTRD no Liver (HepG2) 460996 975 108343871
chr19 461975 461984 SNAI2 JASPAR yes 460996 979 70775971
chr19 461975 461985 TCF4 JASPAR yes 460996 979 70775972
chr19 461977 461986 ZEB1 JASPAR yes 460996 981 70775973
chr19 461979 461984 SP1 TRANSFAC yes 460996 983 70775974
chr19 461980 461990 ZNF740 JASPAR yes 460996 984 70775975
chr19 461981 461986 TFAP2A TRANSFAC yes 460996 985 70775976
chr19 461981 461987 MZF1 JASPAR yes 460996 985 70775977
chr19 461981 462002 ZNF263 JASPAR yes 460996 985 70775978
chr19 461982 462285 ZNF274 GTRD no Bone Marrow (K562) 460996 986 108343872
chr19 461983 461989 MAZ TRANSFAC yes 460996 987 70775979
chr19 461983 461994 E2F6 JASPAR yes 460996 987 70775980
chr19 461985 461993 SP1 TRANSFAC yes 460996 989 70775981
chr19 461985 462006 ZNF263 JASPAR yes 460996 989 70775982
chr19 461985 462591 P63 GTRD no Skin (Keratinocyte) 460996 989 108343873
chr19 461987 461993 MAZ TRANSFAC yes 460996 991 70775983
chr19 461987 461998 E2F6 JASPAR yes 460996 991 70775984
chr19 461989 461997 SP1 TRANSFAC yes 460996 993 70775985
chr19 461989 461999 SP1 JASPAR yes 460996 993 70775986
chr19 461991 461997 MAZ TRANSFAC yes 460996 995 70775987
chr19 461993 462317 ZNF143 ENCODE Uniform TFBS no Embryonic Stem Cell Line (H1-hESC) 460996 997 108343874
chr19 461996 462016 ESR1 JASPAR yes 460996 1000 70775988
chr19 461998 462493 ZNF274 GTRD no Bone Marrow (K562) 460996 1002 108343875
chr19 462004 462013 THAP1 JASPAR yes 460996 1008 70775989
chr19 462006 462015 TFAP2A JASPAR yes 460996 1010 70775990
chr19 462009 462665 P63 GTRD no Skin (Keratinocyte) 460996 1013 108343876
chr19 462016 462026 CUX1 JASPAR yes 460996 1020 70775991
chr19 462016 462026 CUX2 JASPAR yes 460996 1020 70775992
chr19 462018 462522 ZZZ3 ENCODE Uniform TFBS no Cervix (HeLa-S3) 460996 1022 108343877
chr19 462021 462456 ZBTB33 GTRD no Lung (A549) 460996 1025 108343878
chr19 462022 462226 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 460996 1026 108343879
chr19 462027 462262 ZNF274 GTRD no Liver (HepG2) 460996 1031 108343880
chr19 462030 462045 JUND JASPAR yes 460996 1034 70775993
chr19 462030 462377 ZNF274 GTRD no Bone Marrow (K562) 460996 1034 108343881
chr19 462050 462064 ZIC1 JASPAR yes 460996 1054 70775994
chr19 462050 462065 ZIC4 JASPAR yes 460996 1054 70775995
chr19 462052 462057 SP1 TRANSFAC yes 460996 1056 70775996
chr19 462053 462066 TFAP2A JASPAR yes 460996 1057 70775997
chr19 462053 462066 TFAP2B JASPAR yes 460996 1057 70775998
chr19 462053 462066 TFAP2C JASPAR yes 460996 1057 70775999
chr19 462054 462063 TFAP2A JASPAR yes 460996 1058 70776000
chr19 462054 462744 ZNF143 GTRD no Epithelial (MCF-7) 460996 1058 108343882
chr19 462059 462080 ZNF263 JASPAR yes 460996 1063 70776001
chr19 462060 462065 SP1 TRANSFAC yes 460996 1064 70776002
chr19 462060 462067 SP1 TRANSFAC yes 460996 1064 70776003
chr19 462060 462070 SP1 JASPAR yes 460996 1064 70776004
chr19 462060 462081 ZNF263 JASPAR yes 460996 1064 70776005
chr19 462063 462188 ZNF274 ENCODE Uniform TFBS no Bone Marrow (K562) 460996 1067 108343883
chr19 462065 462086 ZNF263 JASPAR yes 460996 1069 70776006
chr19 462068 462078 SP1 JASPAR yes 460996 1072 70776007
chr19 462068 462089 ZNF263 JASPAR yes 460996 1072 70776008
chr19 462071 462076 SP1 TRANSFAC yes 460996 1075 70776009
chr19 462072 462082 ZNF740 JASPAR yes 460996 1076 70776010
chr19 462074 462083 SP1 TRANSFAC yes 460996 1078 70776011
chr19 462074 462084 SP1 JASPAR yes 460996 1078 70776012
chr19 462075 462084 SP1 TRANSFAC yes 460996 1079 70776013
chr19 462076 462082 MAZ TRANSFAC yes 460996 1080 70776014
chr19 462076 462659 ZNF143 GTRD no Epithelial (MCF-7) 460996 1080 108343884
chr19 462120 462132 HES5 JASPAR yes 460996 1124 70776015
chr19 462120 462132 HES7 JASPAR yes 460996 1124 70776016
chr19 462121 462131 HEY1 JASPAR yes 460996 1125 70776017
chr19 462121 462131 HEY2 JASPAR yes 460996 1125 70776018
chr19 462138 462149 NRF1 JASPAR yes 460996 1142 70776019
chr19 462138 462409 ZNF274 GTRD no Bone Marrow (K562) 460996 1142 108343885
chr19 462143 462154 NRF1 JASPAR yes 460996 1147 70776020
chr19 462144 462156 HINFP JASPAR yes 460996 1148 70776021
chr19 462150 462161 E2F4 JASPAR yes 460996 1154 70776022
chr19 462158 463216 TCF7L2 GTRD no Colon (HCT116) 460996 1162 108343886
SNPs associated with SHC2[ENSG00000129946.6], confirmed by eQTL
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Chrom. Position dbSNP ID Reference Allele Alternative Allele Distance between TSS and SNP Tissue q Value id More
chr19 460025 rs11669451 A G,T 0 Esophagus 1.32958e-09 5363960
chr19 460292 rs199827975 TC T 0 Esophagus 1.67849e-18 5363970
chr19 483461 rs35033930 T C 22465 Esophagus 1.95568e-07 5364136
chr19 460292 rs199827975 TC T 0 Spleen 2.29553e-06 5363970
chr19 484650 rs758499 T C,G 23654 Ovary 0.0201174 5364174
chr19 1263299 rs968698 A C 802303 Uterus 0.291141 5373980
Details of SHC2[ENSG00000129946.6]
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Genomic Location chr19:416583-460996[-]
TSS 460996
Gene Name SHC2
Ensembl ID ENSG00000129946.6
ENTREZID 25759
Uniprot
P98077
Protein Name
SHC-transforming protein 2
Expression levels of SHC2[ENSG00000129946.6]
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