EnhancerDB
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Enhancers that regulate PCSK9[ENSG00000169174.9]
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Chrom. Start End Enhancer ID TSS of gene Distance between enhancer and TSS Tissues that enhancer appears More
chr1 55397805 55407955 enh11877 55505221 97266
Prostate (PC-3) Brain (SK-N-MC) Large Intestine Prostate (RWPE1) Esophagus Astrocyte Bone (Osteoblast) Placenta Lung (PC-9) Epithelial (MCF-7)
chr1 55408539 55413435 enh49768 55505221 91786
Prostate (PC-3) Cervix (HeLa-S3) Prostate (RWPE1) Large Intestine Esophagus Lung (PC-9)
chr1 55411305 55411465 vista1673 55505221 93756
VISTA
chr1 55413725 55423635 enh11878 55505221 81586
Prostate (PC-3) Cervix (HeLa-S3) Prostate (RWPE1) Ovary Esophagus Astrocyte Bone (Osteoblast) Placenta Lung (PC-9) Pancreas Muscle (Myotube) Uterus Heart
chr1 55413962 55414227 vista1674 55505221 90994
VISTA
chr1 55414845 55415038 vista1675 55505221 90183
VISTA
chr1 55418708 55418921 vista1676 55505221 86300
VISTA
chr1 55426360 55441461 enh371 55505221 63760
Skin (Keratinocyte) Prostate (PC-3) Cervix (HeLa-S3) Prostate (RWPE1) Esophagus Muscle (A673) Placenta Colon (HCT116) Blood (Karpas-422) Lung (PC-9) Muscle (Myoblast) Spleen Muscle (Myotube) Neural Stem Cells (H9) Stomach
chr1 55431735 55431939 vista1677 55505221 73282
VISTA
chr1 55436992 55437436 vista1678 55505221 67785
VISTA
chr1 55445592 55445683 vista1679 55505221 59538
VISTA
chr1 55453225 55457495 enh87606 55505221 47726
Pancreas Lung (PC-9)
chr1 55461514 55461717 vista1680 55505221 43504
VISTA
chr1 55485564 55490164 enh61846 55505221 15057
Bone Marrow (K562) Cervix (HeLa-S3) Prostate (RWPE1) Esophagus Epithelial (MCF-7)
chr1 55506956 55507037 vista1681 55505221 1735
VISTA
chr1 55513625 55517775 enh74218 55505221 8404
Muscle (A673)
chr1 55591745 55595895 enh79038 55505221 86524
Prostate (PC-3)
chr1 55594097 55594408 vista1682 55505221 88876
VISTA
Transcript facotrs that regulate PCSK9[ENSG00000169174.9]
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Chrom. Start End TF name Source Predicted site? Tissue TSS of gene Distance between TFBS and gene id More
chr1 55505847 55508119 ZBTB33 GTRD no Lung (A549) 55505221 626 107805498
chr1 55505901 55508220 ZBTB33 GTRD no Lung (A549) 55505221 680 107805499
chr1 55506083 55508261 ZBTB33 GTRD no Lung (A549) 55505221 862 107805500
chr1 55506215 55507756 ZBTB33 GTRD no Lung (A549) 55505221 994 107805501
chr1 55506219 55508270 ZBTB33 GTRD no Lung (A549) 55505221 998 107805502
chr1 55506261 55508248 ZNF274 GTRD no Cervix (HeLa-S3) 55505221 1040 107805503
chr1 55506303 55507920 ZBTB33 GTRD no Lung (A549) 55505221 1082 107805504
chr1 55506412 55507510 ZNF274 GTRD no Cervix (HeLa-S3) 55505221 1191 107805505
chr1 55506412 55507524 ZNF274 GTRD no Cervix (HeLa-S3) 55505221 1191 107805506
chr1 55506465 55507682 ZBTB33 GTRD no Lung (A549) 55505221 1244 107805507
chr1 55506482 55507706 ZBTB33 GTRD no Lung (A549) 55505221 1261 107805508
chr1 55506508 55507474 ZNF274 GTRD no Cervix (HeLa-S3) 55505221 1287 107805509
chr1 55506508 55507785 ZBTB33 GTRD no Lung (A549) 55505221 1287 107805510
chr1 55506522 55507226 ZNF274 GTRD no Cervix (HeLa-S3) 55505221 1301 107805511
chr1 55506526 55507022 ZNF217 ENCODE Uniform TFBS no Epithelial (MCF-7) 55505221 1305 107805512
chr1 55506531 55507996 ZNF274 GTRD no Cervix (HeLa-S3) 55505221 1310 107805513
chr1 55506537 55507706 ZBTB33 GTRD no Lung (A549) 55505221 1316 107805514
chr1 55506551 55507574 ZBTB33 GTRD no Lung (A549) 55505221 1330 107805515
chr1 55506569 55507513 ZNF274 GTRD no Cervix (HeLa-S3) 55505221 1348 107805516
chr1 55506570 55507960 ZBTB33 GTRD no Lung (A549) 55505221 1349 107805517
chr1 55506626 55507955 ZBTB33 GTRD no Lung (A549) 55505221 1405 107805518
chr1 55506627 55507652 ZBTB33 GTRD no Lung (A549) 55505221 1406 107805519
chr1 55506632 55507979 ZBTB33 GTRD no Lung (A549) 55505221 1411 107805520
chr1 55506655 55507639 ZBTB33 GTRD no Lung (A549) 55505221 1434 107805521
chr1 55506664 55507382 ZBTB33 GTRD no Lung (A549) 55505221 1443 107805522
chr1 55506664 55507440 ZNF274 GTRD no Cervix (HeLa-S3) 55505221 1443 107805523
chr1 55506684 55507332 ZNF274 GTRD no Cervix (HeLa-S3) 55505221 1463 107805524
chr1 55506712 55507394 ZNF274 GTRD no Cervix (HeLa-S3) 55505221 1491 107805525
chr1 55506716 55507439 ZNF274 GTRD no Cervix (HeLa-S3) 55505221 1495 107805526
chr1 55506733 55507190 ZNF274 GTRD no Cervix (HeLa-S3) 55505221 1512 107805527
chr1 55506760 55507231 ZBTB33 GTRD no Lung (A549) 55505221 1539 107805528
chr1 55506774 55507412 ZBTB33 GTRD no Lung (A549) 55505221 1553 107805529
chr1 55506774 55507690 ZBTB33 GTRD no Lung (A549) 55505221 1553 107805530
chr1 55506789 55507626 ZBTB33 GTRD no Lung (A549) 55505221 1568 107805531
chr1 55506790 55507721 ZBTB33 GTRD no Lung (A549) 55505221 1569 107805532
chr1 55506804 55507163 ZBTB33 GTRD no Lung (A549) 55505221 1583 107805533
chr1 55506807 55507361 ZBTB33 GTRD no Lung (A549) 55505221 1586 107805534
chr1 55506814 55507703 ZBTB33 GTRD no Lung (A549) 55505221 1593 107805535
chr1 55506828 55507325 ZNF274 GTRD no Cervix (HeLa-S3) 55505221 1607 107805536
chr1 55506830 55507514 ZBTB33 GTRD no Lung (A549) 55505221 1609 107805537
chr1 55506879 55507463 ZNF143 GTRD no Epithelial (MCF-7) 55505221 1658 107805538
chr1 55506906 55507388 ZNF143 GTRD no Epithelial (MCF-7) 55505221 1685 107805539
chr1 55506909 55507307 ZBTB33 GTRD no Lung (A549) 55505221 1688 107805540
chr1 55506960 55506964 NFE TRANSFAC yes 55505221 1739 118294001
chr1 55506978 55506992 TLX1 JASPAR yes 55505221 1757 118294002
chr1 55506979 55507698 ZBTB33 GTRD no Lung (A549) 55505221 1758 107805541
chr1 55506984 55506990 YY1 JASPAR yes 55505221 1763 118294003
chr1 55506987 55507474 ZNF143 GTRD no Epithelial (MCF-7) 55505221 1766 107805542
chr1 55506989 55507010 MAFG JASPAR yes 55505221 1768 118294004
chr1 55506995 55507450 ZNF274 GTRD no Cervix (HeLa-S3) 55505221 1774 107805543
chr1 55506996 55507007 BATF JASPAR yes 55505221 1775 118294005
chr1 55507015 55507028 ELF3 JASPAR yes 55505221 1794 118294006
chr1 55507016 55507029 ELF1 JASPAR yes 55505221 1795 118294007
chr1 55507019 55507024 ETS2 TRANSFAC yes 55505221 1798 118294008
SNPs associated with PCSK9[ENSG00000169174.9], confirmed by eQTL
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Chrom. Position dbSNP ID Reference Allele Alternative Allele Distance between TSS and SNP Tissue q Value id More
chr1 55880102 rs149689167 T C 349577 Esophagus 0.243626 326427
chr1 55514182 rs535471 T C 0 Pancreas 0.0452351 324265
chr1 56097676 rs6681647 C T 567151 Ovary 0.361023 328355
chr1 55673671 rs2454213 G A 143146 Adrenal 0.304442 324686
Details of PCSK9[ENSG00000169174.9]
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Genomic Location chr1:55505221-55530525[+]
TSS 55505221
Gene Name PCSK9
Ensembl ID ENSG00000169174.9
ENTREZID 255738
Uniprot
Q8NBP7
Protein Name
Proprotein convertase subtilisin/kexin type 9
Expression levels of PCSK9[ENSG00000169174.9]
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